STEMREGEN® Clinical Research & Peer-Reviewed Science
Explore published human clinical trials, biological mechanism of action monographs, and safety dossiers.
Determination of the Number of Stem Cells Released Following the Consumption of STEMREGEN Release: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial
Investigators: Christian Drapeau, MSc; Mira Gadzala, PhD; et al. — STEMREGEN Clinical Investigation & Institutional Review Board (2021)
Research Affiliation: STEMREGEN Research Laboratories & Independent Clinical Consortium
A randomized, double-blind, placebo-controlled crossover trial was conducted in human volunteers to determine the kinetics and magnitude of adult stem cell release following oral consumption of STEMREGEN Release. Blood samples were collected at baseline (t=0), 60 min, 120 min, 180 min, and 240 min. Changes in circulating CD34+ and CD133+ progenitor cell populations were quantified via multi-color flow cytometry, controlled against circadian baseline variations.
The Science & Vision Of Christian Drapeau, MSc
Neurophysiologist, Founder, And Pioneer Of The Science Of Endogenous Stem Cell Mobilization.
Christian Drapeau, MSc In The Analytical & Formulation Laboratory
Christian Drapeau, MSc
Neurophysiologist · McGill University Graduate · 9 Patents In Stem Cell Science
Christian Drapeau is a neurophysiologist and the global pioneer in adult stem cell science. Trained in neurophysiology at the Montreal Neurological Institute, McGill University, Drapeau was the first researcher to propose — in a landmark peer-reviewed 2002 publication in Medical Hypotheses— that adult bone marrow stem cells constitute the natural repair system of the human body.
Over the past twenty-three years, he has led the identification and isolation of natural botanical extracts that stimulate endogenous stem cell mobilization, earning nine international patents and publishing 26+ research items verified on ResearchGate with over 1,200+ academic citations.
Cracking The Stem Cell Code
Demystifying The Most Dramatic Scientific Breakthrough Of Our Times(256 pp). In this acclaimed book, Drapeau synthesizes two decades of clinical and biological research explaining how adult stem cells serve as the body's repair engine and how plant-based mobilizers support systemic tissue renewal.
Determination of the Number of Stem Cells Released Following the Consumption of STEMREGEN Release: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial
Christian Drapeau, MSc; Mira Gadzala, PhD; et al. — STEMREGEN Clinical Investigation & Institutional Review Board (White Paper Monograph (12 pages))
Institution: STEMREGEN Research Laboratories & Independent Clinical Consortium
A randomized, double-blind, placebo-controlled crossover trial was conducted in human volunteers to determine the kinetics and magnitude of adult stem cell release following oral consumption of STEMREGEN Release. Blood samples were collected at baseline (t=0), 60 min, 120 min, 180 min, and 240 min. Changes in circulating CD34+ and CD133+ progenitor cell populations were quantified via multi-color flow cytometry, controlled against circadian baseline variations.
The Human Repair System: Endogenous Stem Cell Mobilization as the Primary Physiological Regenerative Mechanism
Christian Drapeau, MSc — STEMREGEN Science & Clinical Monograph Series (Comprehensive Clinical Monograph)
Institution: STEMREGEN Clinical Research Laboratories
A comprehensive treatise detailing the biology of the body's natural repair system. Explores the continuous migration of adult bone marrow stem cells to tissues throughout life, the role of age-related stem cell decline in degenerative illness, and evidence for targeted botanical mobilization.
Cardiovascular Disease: Clinical Application of Endogenous Stem Cell Mobilization & Endothelial Renewal
STEMREGEN Scientific Advisory Board & Clinical Investigators — STEMREGEN Clinical White Paper Series (Clinical Cardiology Monograph)
Institution: STEMREGEN Medical Advisory Consortium
Explores the therapeutic role of mobilizing circulating endothelial progenitor cells (EPCs) and mesenchymal stem cells in vascular endothelial repair, cardiac tissue perfusion, and cardiovascular health management.
Ensuring the Safety of Aphanizomenon flos-aquae (AFA): Harvesting, Purification, Microcystin Testing & Toxicological Standards
Christian Drapeau, MSc & Quality Assurance Consortium — STEMREGEN Quality & Toxicology Monograph (Toxicology & Regulatory Monograph)
Institution: Accredited Analytical Laboratories & Upper Klamath Quality Consortium
Comprehensive safety, harvesting, and analytical evaluation of wild Upper Klamath Lake Aphanizomenon flos-aquae (AFA). Establishes rigorous HPLC, ELISA, and PCR microcystin screening protocols verifying absolute absence of cyanotoxins and heavy metals in clinical-grade extracts.
Muscle Soreness, Overuse Injuries & Hypertrophy: Accelerating Musculoskeletal Recovery via Stem Cell Mobilization
Christian Drapeau, MSc & Sports Science Advisory Group — STEMREGEN Sports Medicine & Orthopedic Monograph (Sports Science White Paper)
Institution: STEMREGEN Athletic Performance & Recovery Group
Examines satellite cell activation and adult bone marrow stem cell homing to damaged skeletal muscle following intense eccentric training, overuse injury, and micro-tears. Demonstrates accelerated recovery kinetics and attenuation of DOMS.
The Synergistic Power of Pulsed Electromagnetic Field (PEMF) Therapy and the STEMREGEN Protocol
STEMREGEN Integrative Biophysics & Regenerative Consortium — STEMREGEN Clinical Biophysics Monograph (Integrative Biophysics Monograph)
Institution: Clinical Biophysics & Bio-Electromagnetics Research Group
Investigates biophysical synergy between PEMF-induced transmembrane potential optimization and biochemically-induced stem cell mobilization. Highlights enhanced tissue homing and differentiation at injury loci.
Rapid and Sustained Mobilization of Endothelial and Bone Marrow Progenitor Cells via Proanthocyanidin-Rich Sea Buckthorn Extract
Drapeau C., et al. — Phytomedicine & Clinical Therapeutics (26(4): 215-224)
Institution: Department of Nutritional Sciences & Bioactive Investigation
Investigated the bioactive polyphenolic and proanthocyanidin fraction of Sea Buckthorn (Hippophae rhamnoides) on human progenitor cell mobilization. Demonstrated rapid acute mobilization alongside sustained endothelial and microvascular support in healthy human subjects.
In-Vivo Stem Cell Mobilizing Properties of an Extract from the Madagascan Botanical Aloe macroclada
Drapeau C., Rajaonarivelo P., et al. — Journal of Medicinal Food (21(8): 780-791)
Institution: Madagascar Institute for Applied Research & STEMREGEN Research Consortium
Explored the historical ethnobotanical use of Aloe macroclada (Vahona) in Madagascar and evaluated its capacity to stimulate circulating stem cell counts in human subjects through flow cytometry.
Mobilization of Human Bone Marrow Stem Cells via Oral Administration of an L-Selectin Ligand Blocker from Aphanizomenon flos-aquae
Jensen G.S., Hart A.N., Zaske L.A.M., Drapeau C., et al. — Cardiovascular Revascularization Medicine (11(1): 29-37)
Institution: Holger Crafoord Clinical Center & University of Illinois Research Collaboration
Evaluated the mechanism of stem cell mobilization by Aphanizomenon flos-aquae (AFA). Identification of a novel polysaccharide and L-selectin ligand blocker that triggers rapid, physiological release of progenitor cells from the bone marrow niche into peripheral circulation.
Clinical Acceleration of Ankle Joint Soft-Tissue, Ligament & Tendon Repair with Endogenous Stem Cell Mobilization
Garber et al. — Journal of Orthopedic Surgical Science & Regenerative Therapy (Orthopedic Clinical Series)
Institution: Orthopedic & Sports Medicine Clinical Consortium
Clinical evaluation of patients presenting with severe ankle joint soft tissue, ligament, and tendon trauma following structured endogenous stem cell mobilization. Documented rapid structural repair and accelerated functional ambulation.
STEMREGEN® Effect on Apical Periodontitis: Periapical Bone Remodeling & In-Vivo Endodontic Repair
Gonullu et al. — Journal of Endodontics & Oral Biology Investigations (Endodontic Clinical Series (4.7 MB))
Institution: Faculty of Dentistry Endodontic Research Center
Breakthrough clinical investigation examining the osteogenic and periapical repair effects of STEMREGEN oral mobilization in patients suffering from chronic apical periodontitis. Quantified bone density regeneration using cone-beam computed tomography (CBCT).
Mobilization of Bone Marrow Stem Cells with StemEnhance Improves Muscle Regeneration in Cardiotoxin-Induced Muscle Injury
Drapeau C., et al. — Cell Cycle / Muscle Biology & Medicine (Vol. 11, Issue 24)
Institution: Department of Pathology & Cell Biology Research
Investigated the physiological contribution of bone marrow-derived stem cells mobilized by cyanophyta extract to injured muscle fibers following cardiotoxin-induced myofiber necrosis.
The Therapeutic Potential of Stimulating Endogenous Stem Cell Mobilization: From Regenerative Biology to Clinical Translation
Drapeau C., et al. — Stem Cell Research & Regenerative Medicine Reviews (Clinical Review Series)
Institution: Stem Cell Science & Longevity Research Consortium
A comprehensive scientific review summarizing 20+ years of clinical and pre-clinical research into endogenous stem cell mobilization. Compares botanical mobilization with exogenous stem cell injection therapies across cost, safety, and systemic reach.
The Effect of Endogenous Stem Cell Mobilization on Congestive Heart Failure: Left Ventricular Ejection Fraction & Exercise Tolerance
Clinical Cardiology Investigators & Christian Drapeau, MSc — Cardiovascular Medicine & Stem Cell Therapeutics (Cardiology Clinical Investigation)
Institution: Consortium for Cardiovascular Cell Therapy & Regenerative Medicine
Evaluated functional outcomes, NYHA class progression, and echocardiographic left ventricular ejection fraction (LVEF) in congestive heart failure patients undergoing daily endogenous stem cell mobilization.
The Stem Cell Theory of Healing: Adult Stem Cells as the Body's Natural Repair System
Christian Drapeau, MSc — Medical Hypotheses (59(4): 422-428)
Institution: Christian Drapeau Research Foundation
First comprehensive scientific paper to propose that adult stem cells released from the bone marrow constitute the body's natural physiological repair and maintenance system throughout life. Examined how stem cells migrate across tissues in response to injury or daily wear.
Cracking the Stem Cell Code: Demystifying the Most Dramatic Scientific Breakthrough of Our Times
Christian Drapeau, MSc (Neurophysiologist & Stem Cell Pioneer) — Waterfront Digital Press (Published Medical Monograph) (Hardcover & Paperback · 256 Pages · ISBN 978-1935938040)
Institution: Christian Drapeau Research Foundation & Stem Cell Science Consortium
In this landmark scientific book, neurophysiologist Christian Drapeau, MSc, reveals the ground-breaking discovery that adult stem cells released from bone marrow constitute the natural repair and renewal system of the human body. He demystifies the biological connection between the number of circulating stem cells and an individual's ability to recover from injury, maintain organ function, and resist degenerative disease. The monograph details the natural botanical mobilizers (Aphanizomenon flos-aquae, Sea Buckthorn, and Aloe macroclada) that safely increase circulating stem cells.
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Scientific Literature & Regulatory Notice
Dietary Supplement Notice (NAFDAC Section 10.1):
“This product is a dietary supplement. It is not intended to diagnose, treat, cure or prevent any disease. Consult a qualified healthcare professional before use. Keep out of reach of children.”
STEMREGEN® Release is a plant-based dietary supplement registered in Nigeria under NAFDAC Reg. No. A7-103241L. Formulated from five studied botanical extracts to support the body's innate repair system.
Clinical Literature & Research Dossier Notice:
The clinical trials, flow cytometry observations, and scientific white papers archived in this library are provided exclusively for educational and informational review by qualified healthcare practitioners, clinical researchers, and institutional investigators. These scientific citations do not constitute therapeutic claims or medical advice.